Peptide Publications Archive
Quorum Sensing Redux
Tal-Gan Lab
Streptococcus constellatus, a member of the Streptococcus anginosus group, SAG, is an opportunistic pathogen commonly found in the human oral and gastrointestinal microbiota. While …
Macrocyclic Peptide Antibiotics
van der Donk Lab
Ribosomally synthesized and posttranslationally modified peptides, RiPPs, represent one of the most structurally diverse classes of natural products, yet many RiPP families remain biosynthetically uncharacterized...
Conjugation Chemistry
Kwon Lab
Traumatic brain injury, TBI, remains a profound and unresolved clinical challenge, responsible for long-term disability in both civilian and military populations. The lack of effective …
Grafted Coiled Coils
Andrew J. Lab
Protein–protein interactions, PPIs, are fundamental to cellular regulation, yet targeting them therapeutically remains challenging due to their extensive, shallow interfaces. Peptides offer an attractive solution, …
Efficient siRNA Delivery
Anders Lab
In this collaborative study, published in Bioconjugate Chemistry by researchers from the Dahlén group at Astra-Zeneca, Gothenburg, Sweden, and the Andaloussi team at the Karolinska …
Potent Antifungal Lipopeptide
Süssmuth Lab
In this study, researchers from the Süssmuth group at the Technische Universität Berlin, published in the Journal of the American Chemical Society, elucidated the …
Oxidative Peptide Coupling
Proulx Lab
This study demonstrates that a key determinant of this reactivity is the choice of solvent. By shifting from aqueous buffer to a mixed organic solvent …
Molecular Scaffolds
Craik Lab
This comprehensive review from the labs of David Craik and Lara Malins at Australian Research Council Centre of Excellence for Innovations in Peptide and Protein …
Quorum Sensing
Tal-Gan Lab
Streptococcus cristatus, a commensal member of the oral microbiota and recently reclassified from Streptococcus oligofermentans, has emerged as a promising candidate in the …
From Hydrogel to Crystal
Schneider Lab
Published in the Journal of the American Chemical Society, researchers in the lab of Dr. Joel P. Schneider at NIH, have unveiled a groundbreaking …
Sequence Architecture
Woolfson Lab
The Woolfson Lab continues to break new ground in de novo protein design with the successful creation of mixed-charge A3B3 heterohexameric α-helical …
Versatile Precursors
Mitchell Lab
Cyclopropane-containing amino acids, prized for their conformational rigidity and stability, are of increasing interest in therapeutic peptide development and antimicrobial drug discovery. A recent study …