Herein, a noninteracting multiphase molecular assembly approach is developed to crystallize tofacitinib, a potent JAK1/3 inhibitor, within a shearthinning self-assembled fibrillar peptide hydrogel network...

Church et al. report a tunable chemical genetics approach for enhancing genetic code expansion in different wild-type bacterial strains..

Abundant n → π* interactions between adjacent backbone carbonyl groups are predicted to play an important role in dictating the structure of proteins...

Herein, Wang et al. present a photoredox-catalyzed asymmetric method for the preparation of enantiopure β-thiolated/selenolated amino acids using a simple chiral auxiliary...

Given the ongoing SARS-CoV-2 pandemic, identification of immunogenic targets against the coronavirus spike glycoprotein will provide crucial advances towards the development of diagnostic tools...

In this review, the researchers summarize peptide and peptide based therapeutics that target one main entry pathway of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

This colloborative work between the Garner and Kritzer labs shows their continued efforts to develop and characterization of a cell-penetrant lactam stapled peptide for targeting cellular eIF4E...

Researchers at the University of Sydney have shown that the evasin protein ACA-01 from the Amblyomma cajennense tick can be posttranslationally sulfated at two tyrosine residues...

This publication shows that micelle-assisted reaction can facilitate native chemical ligations between a peptide-thioester and a Cys-peptide modified by a lipid-like moiety...