American Peptide Society

Members of the Arora lab constructed a synthetic Sos protein mimic that engages the wild-type and oncogenic forms of nucleotide-bound Ras and modulates downstream kinase signaling...

In this conspectus, the authors give an overview of the early history of the rippled β-sheet and provide a detailed structural description/definition of this motif...

Despite recent success in computational design of structured cyclic peptides, de novo design of cyclic peptides that bind to any protein functional site remains difficult...

The design of peptides that assemble in membranes to form functional ion channels is challenging. Specifically, hydrophobic interactions must be...

Herein, researchers in the Kaumaya lab describe a novel PD-1 B-cell peptide epitope vaccine (amino acid 92–110; PD1-Vaxx) linked to a measles virus fusion peptide...

In this article, Professor Pravin Kaumaya reviews his lab's approaches and strategies that focus on B-cell epitope cancer vaccines...

The production of peptides as active pharmaceutical ingredients (APIs) by recombinant technologies is of emerging interest. A reliable production platform, however...

Chemical protein synthesis is a powerful avenue for accessing homogeneously modified proteins, but access to large targets has proved challenging...

Herein is described a divergent late-stage approach to generating macrocyclic peptide libraries with unnatural pharmacophores from readily available starting material...