Peptide Publications Archive

Peptide Modifications

Peptide Modifications

Phan Lab

Ribosomally synthesized and post-translationally modified peptides, RiPPs, represent an expanding class of natural products distinguished by their extensive post-translational modifications. Among the enzymatic systems...

Genome Mining

Genome Mining

Agarwal Lab

Brominated intermediates have long been favored in organic synthesis for their chemical versatility, particularly in transition-metal-assisted bond-forming reactions. The Agarwal and van der Donk study …

Backbone Editing

Backbone Editing

Schepartz Lab

The ability to precisely manipulate the peptide backbone remains one of the fundamental challenges in biomolecular engineering. While ribosomal translation and peptide synthesis methods allow …

Super-Res Microscopy

Super-Res Microscopy

Guha Lab

Researchers in the Samit Guha Group at Jadavpur University, Kolkata, India, published in Bioconjugate Chemistry, report a groundbreaking approach to cancer imaging...

Selective Cyclization

Selective Cyclization

Liu Lab

To address the limitations of current methods for peptide macrocyclization, which often rely on nonspecific small-molecule linkers...

Molecular Flasks

Molecular Flasks

Woolfson Lab

To address the formidable challenge of binding and orienting multiple small molecules for directed chemical reactions, researchers in the Woolfson and Oliver groups at the …

Yeast CICLOPPS

Yeast CICLOPPS

Knudsen Lab

Researchers in the Knudsen Group at the University of Aarhus, Denmark, published in Biochemistry, report the construction of a Saccharomyces cerevisiae-specific SICLOPPS library …

Graspetides

Graspetides

Ding Lab

Published in ACS Chemical Biology, researchers in the Ding Group at the University of Florida, reconstructed prunipeptin biosynthesis from Streptomyces coelicolor...

Metallo-Azapeptides

Metallo-Azapeptides

Proulx Lab

Published in the Journal of the American Chemical Society, researchers in the Proulx group at the North Carolina State University at Raleigh, present the …