W. Seth Horne

W. Seth Horne

W. Seth Horne
Associate Professor
University of Pittsburgh

Professional Positions

2015 - present, University of Pittsburgh, Associate Professor, Department of Chemistry
2009 - 2015, University of Pittsburgh, Assistant Professor, Department of Chemistry


2005 - 2009, NIH Postdoctoral Fellow with Prof. Samuel H. Gellman, University of Wisconsin Madison
2000 - 2005, Ph.D. Chemistry with Prof. M. Reza Ghadiri, The Scripps Research Institute
1996 - 2000, B.S. Chemistry, Texas A&M University

APS Service

2015 - 2017, Nominating Committee Chair
2013- 2015, Nominating Committee

Awards & Honors

2016, University of Pittsburgh Chancellor’s Distinguished Research Award
2014, Thieme Chemistry Journal Award
2012, National Science Foundation CAREER Award
2006, National Institutes of Health Postdoctoral Fellowship
2001, National Science Foundation Graduate Research Fellowship
1999, Goldwater Scholar

Research Interest

Research in the Horne Lab is focused on molecules that are inspired by peptides and proteins but expand beyond natural constraints of covalent connectivity. Through work in this area to date, we have shown how systematic alteration of backbone composition, side-chain identity, and chain topology can be used to control folding behavior, direct self-assembly, provide fundamental insights into biological systems, and create artificial mimics of natural folds and functions.

Personal Statement

As an active researcher in the area of peptide chemistry for almost two decades, I have long been familiar with APS and its work. It has been my pleasure to serve the society in the past on standing committees and as a co-organizer (with Philip Dawson and Stephen Kent) of the 6th Chemical Protein Synthesis Meeting, a satellite of the 2015 American Peptide Symposium in Orlando, Florida. If elected to the position of Councilor, I look forward to the opportunity to expand my involvement and help advance the society’s mission to support and promote the global community of researchers in peptide and protein science.

FASEB logo

FASEB Capitol Hill Day

FASEB Capitol Hill Day

On Tuesday (March 9th) and Thursday (March 11th), APS FASEB representative Dr. Mark Distefano along with other FASEB representatives and staff met with congressional staff members from both the House of Representatives and Senate to encourage them to increase the budgets for both NIH and NSF.

Save the Date

Save the Date

Please join us for the 27th American Peptide Symposium to be held June 11-16, 2022 in the beautiful mountain town of Whistler, Canada. Note this event was postponed a year due to COVID-19. The meeting program will cover a broad range of peptide-related topics and provides an excellent opportunity to network with scientists from around the world.