W. Seth Horne

W. Seth Horne

W. Seth Horne
Associate Professor
University of Pittsburgh

Professional Positions

2015 - present, University of Pittsburgh, Associate Professor, Department of Chemistry
2009 - 2015, University of Pittsburgh, Assistant Professor, Department of Chemistry


2005 - 2009, NIH Postdoctoral Fellow with Prof. Samuel H. Gellman, University of Wisconsin Madison
2000 - 2005, Ph.D. Chemistry with Prof. M. Reza Ghadiri, The Scripps Research Institute
1996 - 2000, B.S. Chemistry, Texas A&M University

APS Service

2015 - 2017, Nominating Committee Chair
2013- 2015, Nominating Committee

Awards & Honors

2016, University of Pittsburgh Chancellor’s Distinguished Research Award
2014, Thieme Chemistry Journal Award
2012, National Science Foundation CAREER Award
2006, National Institutes of Health Postdoctoral Fellowship
2001, National Science Foundation Graduate Research Fellowship
1999, Goldwater Scholar

Research Interest

Research in the Horne Lab is focused on molecules that are inspired by peptides and proteins but expand beyond natural constraints of covalent connectivity. Through work in this area to date, we have shown how systematic alteration of backbone composition, side-chain identity, and chain topology can be used to control folding behavior, direct self-assembly, provide fundamental insights into biological systems, and create artificial mimics of natural folds and functions.

Personal Statement

As an active researcher in the area of peptide chemistry for almost two decades, I have long been familiar with APS and its work. It has been my pleasure to serve the society in the past on standing committees and as a co-organizer (with Philip Dawson and Stephen Kent) of the 6th Chemical Protein Synthesis Meeting, a satellite of the 2015 American Peptide Symposium in Orlando, Florida. If elected to the position of Councilor, I look forward to the opportunity to expand my involvement and help advance the society’s mission to support and promote the global community of researchers in peptide and protein science.

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Young Investigator Highlight

Young Investigator Highlight

Arunika Ekanayake, member of the Derda lab at the University of Alberta, is one of the winners of the 2022 Schram Young Investigators Oral Presentation Competition. She presented her work at the American Peptide Society Symposium in Whistler, B.C., Canada this past June....

Save the Date

Save the Date

Consider joining us 'at the peptide frontier' for the next summer's American Peptide Symposium. Co-chairs, Rob Garbaccio and David Chenoweth, are planning a terrific scientific program intertwined with networking opportunities and, as always, lots of fun.